nope, if its disc based, you need the disc to run the app, same is true for dumping games off of discs.
you need the disc to have the console start the game, the console decrypts the official pkg contained on the disc, then while in this state you can dump the contents of the official pkg, then use that dump to make your own Fake pkg which will NOT require the disc to run. this is the only way currently to do so.